KIRhub 2.0
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Patient Mutation Matcher

Upload or paste a variant list, VCF, or MAF. We'll match each variant against the canonical dataset and rank approved drugs by evidence tier. Research Use Only — not for clinical decision-making.

1. Paste variants

Accepted formats: VCF (with SYMBOL=/HGVSp=), MAF (with Hugo_Symbol/HGVSp_Short), or one variant per line. No data is stored server-side.

No patient data is stored. Every match request is audit-logged. Results are ranked hypotheses based on biochemical inhibition assays — they are not treatment recommendations.