Modules
Workbench tools for browsing the drug-target catalog, comparing drugs, and running clinical-translation flows.
Catalog browsing
Wild-type drug discovery
Rank approved drugs by their inhibition of a single kinase at 1 μM.
Mutant drug discovery
Start from a kinase, browse variants and their drug response.
Cancer lineage essentiality
DepMap essential-kinase counts per lineage with drill-down.
Drug comparison workbench
Compare 2–6 drugs side by side across any kinase subset.
Polypharmacology & selectivity
Dose-response explorer
14 drugs × 10 doses × 369 kinases — curves with fitted IC50, Hill, R².
Polypharmacology network
Bipartite graph of drug↔kinase edges above an inhibition threshold.
Repurposing opportunity engine
Off-label drug-target signals scored by inhibition × selectivity.
Combination therapy recommender
Best 2-drug combos to cover a target set with low off-target overlap.
Clinical translation
Research Use Only · not for clinical decision-making · all calls audit-logged.
Patient mutation matcher
VCF/MAF/list upload → tiered drug recommendations with RUO disclaimers + PHI guardrail.
Clinical trial linker
ClinicalTrials.gov search with timeline view.
Research brief generator
Print-ready report from a patient match; export via browser Save-as-PDF.
EMT volcano
Mesenchymal / epithelial differential expression across 514 kinases.