Cancer lineage essentiality
Essential-kinase counts per cancer lineage (DepMap gene-effect score < -0.5). Click into any lineage to see the mutation landscape.
Lineage ranking
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Lymphoid
177 essential kinases
Lung
176 essential kinases
Bowel
171 essential kinases
CNS/Brain
171 essential kinases
Myeloid
155 essential kinases
Esophagus/Stomach
154 essential kinases
Ovary/Fallopian Tube
154 essential kinases
Head and Neck
147 essential kinases
Skin
140 essential kinases
Breast
137 essential kinases
Pancreas
133 essential kinases
Soft Tissue
132 essential kinases
Peripheral Nervous System
130 essential kinases
Kidney
129 essential kinases
Uterus
126 essential kinases
Biliary Tract
119 essential kinases
Bone
114 essential kinases
Bladder/Urinary Tract
111 essential kinases
Pleura
102 essential kinases
Eye
96 essential kinases
Liver
89 essential kinases
Prostate
78 essential kinases
Thyroid
75 essential kinases
Testis
71 essential kinases
Cervix
69 essential kinases
Ampulla of Vater
60 essential kinases
Vulva/Vagina
49 essential kinases
Other
45 essential kinases
Adrenal Gland
43 essential kinases
Fibroblast
35 essential kinases