Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.

← The Pathway Atlas

The pathology-free tumor map

Derived

All 14,118 tumor samples plotted by their 50-dimensional pathway state, reduced to 2D by PCA. PC1 explains 0.0%; PC2 explains 0.0% of the pathway-state variance.

PC1 (0.0% var)PC2 (0.0% var)

Click any tumor to drill into its GSVA pathway profile. Toggle cancer types in the legend to test pathway-level convergence between tumor types.

Next steps

Compare entropy per cancer type to see which cohorts have narrow vs chaotic pathway profiles. Use the joint pharma-tumor co-embedding to overlay the 92 drugs on this same space.