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ACVR1B(ALK4/ACVR1B)

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UniProt P36896 · PDB · AlphaFold · Substrate: Casein + Mn · Clone: aa 150-505

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 3.30
  • Epithelial log2(TPM+1): 3.84
  • Fold change: -0.53
  • Status: No significant change

Selectivity landscape vs inhibition on ACVR1B

Each point is one of the 92 approved drugs; color = inhibition % on ACVR1B.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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