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CDC42BPG(DMPK2/CDC42BPG)

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UniProt Q6DT37 · PDB · AlphaFold · Substrate: DAPK1tide · Clone: Catalytic domain (aa1-475)

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 0.39
  • Epithelial log2(TPM+1): 2.75
  • Fold change: -2.36
  • Status: Downregulated

Selectivity landscape vs inhibition on CDC42BPG

Each point is one of the 92 approved drugs; color = inhibition % on CDC42BPG.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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