DCLK3(DCAMKL3)
Sign in to save this workspaceUniProt Q9C098 · PDB · AlphaFold · Substrate: Ziptide · Clone: aa345-end
Top inhibitors
| # | Drug | Inhibition | Residual | KISS | Gini |
|---|---|---|---|---|---|
| 1 | Repotrectinib | 79.0% | 21.1% | 84.21 | 0.608 |
| 2 | Darovasertib | 58.4% | 41.6% | 96.99 | 0.719 |
| 3 | Canertinib | 17.7% | 82.3% | 96.49 | 0.671 |
| 4 | Quizartinib | 16.4% | 83.6% | 99.50 | 0.737 |
| 5 | Remibrutinib | 7.6% | 92.4% | 99.50 | 0.721 |
| 6 | Capivasertib | 2.1% | 97.9% | 96.48 | 0.644 |
| 7 | Inavolisib | 1.5% | 98.5% | 100.00 | 0.679 |
Paralog block
No paralog group registered for this kinase.
EMT expression
- Mesenchymal log2(TPM+1): 0.05
- Epithelial log2(TPM+1): 0.10
- Fold change: -0.06
- Status: No significant change
Selectivity landscape vs inhibition on DCLK3
Each point is one of the 92 approved drugs; color = inhibition % on DCLK3.
3D structure
Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.
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