KIRhub 2.0
Sign inResearch Use Only

DYRK1A(DYRK1/DYRK1A)

Sign in to save this workspace

UniProt Q13627 · PDB · AlphaFold · Substrate: DYRKtide · Clone: full-lengthmedium-confidence target

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 4.04
  • Epithelial log2(TPM+1): 3.99
  • Fold change: 0.04
  • Status: No significant change

Selectivity landscape vs inhibition on DYRK1A

Each point is one of the 92 approved drugs; color = inhibition % on DYRK1A.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

Annotations

Sign in to read and post annotations.

Loading…