ERN1(ERN1/IRE1)
Sign in to save this workspaceUniProt O75460 · PDB · AlphaFold · Substrate: MBP · Clone: aa 468-endmedium-confidence target
Top inhibitors
| # | Drug | Inhibition | Residual | KISS | Gini |
|---|
Paralog block
No paralog group registered for this kinase.
EMT expression
- Mesenchymal log2(TPM+1): 2.10
- Epithelial log2(TPM+1): 2.44
- Fold change: -0.34
- Status: No significant change
Selectivity landscape vs inhibition on ERN1
Each point is one of the 92 approved drugs; color = inhibition % on ERN1.
Variants (3)
3D structure
Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.
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