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ERN2(ERN2/IRE2)

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UniProt Q76MJ5 · PDB · AlphaFold · Substrate: MBP · Clone: aa 449-end

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 0.06
  • Epithelial log2(TPM+1): 1.28
  • Fold change: -1.22
  • Status: Downregulated

Selectivity landscape vs inhibition on ERN2

Each point is one of the 92 approved drugs; color = inhibition % on ERN2.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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