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INSRR(IRR/INSRR)

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UniProt P14616 · PDB · AlphaFold · Substrate: AXLtide · Clone: cytoplasmic

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 0.09
  • Epithelial log2(TPM+1): 0.12
  • Fold change: -0.03
  • Status: No significant change

Selectivity landscape vs inhibition on INSRR

Each point is one of the 92 approved drugs; color = inhibition % on INSRR.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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