KIRhub 2.0
Sign inResearch Use Only

KDR(KDR/VEGFR2)

Sign in to save this workspace

UniProt P35968 · PDB · AlphaFold · Substrate: pEY + Mn · Clone: aa 789-1356

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 0.72
  • Epithelial log2(TPM+1): 0.20
  • Fold change: 0.52
  • Status: No significant change

Selectivity landscape vs inhibition on KDR

Each point is one of the 92 approved drugs; color = inhibition % on KDR.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

Annotations

Sign in to read and post annotations.

Loading…