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LTK(TYK1/LTK)

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UniProt P29376 · PDB · AlphaFold · Substrate: ABLtide · Clone: Cytoplasmic (450-864)

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 0.60
  • Epithelial log2(TPM+1): 0.86
  • Fold change: -0.26
  • Status: No significant change

Selectivity landscape vs inhibition on LTK

Each point is one of the 92 approved drugs; color = inhibition % on LTK.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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