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MAP3K5(ASK1/MAP3K5)

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UniProt O99683 · PDB · AlphaFold · Substrate: MBP · Clone: full-length

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 2.42
  • Epithelial log2(TPM+1): 2.36
  • Fold change: 0.06
  • Status: No significant change

Selectivity landscape vs inhibition on MAP3K5

Each point is one of the 92 approved drugs; color = inhibition % on MAP3K5.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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