MAP3K8(COT1/MAP3K8)
Sign in to save this workspaceUniProt P41279 · PDB · AlphaFold · Substrate: MEK1 (K97R) · Clone: aa 30-397
Top inhibitors
| # | Drug | Inhibition | Residual | KISS | Gini |
|---|
Paralog block
No paralog group registered for this kinase.
EMT expression
- Mesenchymal log2(TPM+1): 2.28
- Epithelial log2(TPM+1): 2.45
- Fold change: -0.17
- Status: No significant change
Selectivity landscape vs inhibition on MAP3K8
Each point is one of the 92 approved drugs; color = inhibition % on MAP3K8.
3D structure
Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.
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