MAP4K1(HPK1/MAP4K1)
Sign in to save this workspaceUniProt Q92918 · PDB · AlphaFold · Substrate: MBP · Clone: Catalytic (aa11-346)
Top inhibitors
| # | Drug | Inhibition | Residual | KISS | Gini |
|---|
Paralog block
No paralog group registered for this kinase.
EMT expression
- Mesenchymal log2(TPM+1): 0.53
- Epithelial log2(TPM+1): 1.13
- Fold change: -0.60
- Status: No significant change
Selectivity landscape vs inhibition on MAP4K1
Each point is one of the 92 approved drugs; color = inhibition % on MAP4K1.
3D structure
Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.
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