KIRhub 2.0
Sign inResearch Use Only

MAP4K2(GCK/MAP4K2)

Sign in to save this workspace

UniProt Q12851 · PDB · AlphaFold · Substrate: MBP · Clone: full-length

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 3.11
  • Epithelial log2(TPM+1): 3.41
  • Fold change: -0.30
  • Status: No significant change

Selectivity landscape vs inhibition on MAP4K2

Each point is one of the 92 approved drugs; color = inhibition % on MAP4K2.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

Annotations

Sign in to read and post annotations.

Loading…