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MAP4K4(HGK/MAP4K4)

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UniProt O95819 · PDB · AlphaFold · Substrate: MBP · Clone: full catalytic

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 6.55
  • Epithelial log2(TPM+1): 4.89
  • Fold change: 1.66
  • Status: Upregulated

Selectivity landscape vs inhibition on MAP4K4

Each point is one of the 92 approved drugs; color = inhibition % on MAP4K4.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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