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MARK2(MARK2/PAR-1Ba)

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UniProt Q7KZI7-4 · PDB · AlphaFold · Substrate: CHKtide · Clone: full length

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 3.82
  • Epithelial log2(TPM+1): 4.34
  • Fold change: -0.52
  • Status: No significant change

Selectivity landscape vs inhibition on MARK2

Each point is one of the 92 approved drugs; color = inhibition % on MARK2.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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