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MST1R(RON/MST1R)

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UniProt Q04912 · PDB · AlphaFold · Substrate: Axltide + Mn · Clone: aa 983-1400

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 0.80
  • Epithelial log2(TPM+1): 3.83
  • Fold change: -3.02
  • Status: Downregulated

Selectivity landscape vs inhibition on MST1R

Each point is one of the 92 approved drugs; color = inhibition % on MST1R.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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