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MYLK(MLCK/MYLK)

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UniProt Q15746 · PDB · AlphaFold · Substrate: ZIPtide + Ca-CaM · Clone: Catalytic (aa 1428-1771)

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 5.72
  • Epithelial log2(TPM+1): 1.48
  • Fold change: 4.25
  • Status: Upregulated

Selectivity landscape vs inhibition on MYLK

Each point is one of the 92 approved drugs; color = inhibition % on MYLK.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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