KIRhub 2.0
Sign inResearch Use Only

PDPK1(PDK1/PDPK1)

Sign in to save this workspace

UniProt O15530 · PDB · AlphaFold · Substrate: PDKtide · Clone: full length

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 4.05
  • Epithelial log2(TPM+1): 4.07
  • Fold change: -0.02
  • Status: No significant change

Selectivity landscape vs inhibition on PDPK1

Each point is one of the 92 approved drugs; color = inhibition % on PDPK1.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

Annotations

Sign in to read and post annotations.

Loading…