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PKN1(PKN1/PRK1)

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UniProt Q16512 · PDB · AlphaFold · Substrate: Glycogen Synthase-derived peptide · Clone: full lengthmedium-confidence target

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 5.79
  • Epithelial log2(TPM+1): 5.57
  • Fold change: 0.21
  • Status: No significant change

Selectivity landscape vs inhibition on PKN1

Each point is one of the 92 approved drugs; color = inhibition % on PKN1.

Variants (1)

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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