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PKN2(PKN2/PRK2)

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UniProt Q16513 · PDB · AlphaFold · Substrate: Glycogen Synthase-derived peptide · Clone: full lengthmedium-confidence target

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 4.22
  • Epithelial log2(TPM+1): 4.21
  • Fold change: 0.02
  • Status: No significant change

Selectivity landscape vs inhibition on PKN2

Each point is one of the 92 approved drugs; color = inhibition % on PKN2.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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