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PKN3(PKN3/PRK3)

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UniProt Q6P5Z2 · PDB · AlphaFold · Substrate: SGKtide · Clone: full-lengthmedium-confidence target

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 2.57
  • Epithelial log2(TPM+1): 3.05
  • Fold change: -0.48
  • Status: No significant change

Selectivity landscape vs inhibition on PKN3

Each point is one of the 92 approved drugs; color = inhibition % on PKN3.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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