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UniProt P22694 · PDB · AlphaFold · Substrate: Long S6 Kinase substrate peptide · Clone: full-length

Top inhibitors

MeasuredDerived
#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

MeasuredDerived
  • Mesenchymal log2(TPM+1): 4.11
  • Epithelial log2(TPM+1): 2.87
  • Fold change: 1.25
  • Status: Upregulated

Selectivity landscape vs inhibition on PRKACB

MeasuredDerived

Each point is one of the 92 approved drugs; color = inhibition % on PRKACB.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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