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PRKCZ(PKCzeta)

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UniProt Q05513 · PDB · AlphaFold · Substrate: PKCepsilon Peptide · Clone: full-length

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 1.77
  • Epithelial log2(TPM+1): 3.97
  • Fold change: -2.19
  • Status: Downregulated

Selectivity landscape vs inhibition on PRKCZ

Each point is one of the 92 approved drugs; color = inhibition % on PRKCZ.

Variants (1)

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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