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RPS6KA4(MSK2/RPS6KA4)

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UniProt O75676 · PDB · AlphaFold · Substrate: Crosstide · Clone: full-length

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 4.60
  • Epithelial log2(TPM+1): 4.23
  • Fold change: 0.37
  • Status: No significant change

Selectivity landscape vs inhibition on RPS6KA4

Each point is one of the 92 approved drugs; color = inhibition % on RPS6KA4.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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