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RPS6KB1(p70S6K/RPS6KB1)

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UniProt P23443 · PDB · AlphaFold · Substrate: S6K/Rsk2 peptide 2 · Clone: Catalytic (aa 1-421)

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 4.16
  • Epithelial log2(TPM+1): 4.17
  • Fold change: -0.01
  • Status: No significant change

Selectivity landscape vs inhibition on RPS6KB1

Each point is one of the 92 approved drugs; color = inhibition % on RPS6KB1.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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