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TYRO3(TYRO3/SKY)

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UniProt Q06418 · PDB · AlphaFold · Substrate: pEY + Mn · Clone: Cytoplasmic (451-890)medium-confidence target

Top inhibitors

#DrugInhibitionResidualKISSGini

Paralog block

No paralog group registered for this kinase.

EMT expression

  • Mesenchymal log2(TPM+1): 3.82
  • Epithelial log2(TPM+1): 3.46
  • Fold change: 0.36
  • Status: No significant change

Selectivity landscape vs inhibition on TYRO3

Each point is one of the 92 approved drugs; color = inhibition % on TYRO3.

3D structure

Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.

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