YES1(YES/YES1)
Sign in to save this workspaceUniProt P07947 · PDB · AlphaFold · Substrate: pEY · Clone: full length
Top inhibitors
| # | Drug | Inhibition | Residual | KISS | Gini |
|---|
Paralog block
No paralog group registered for this kinase.
EMT expression
- Mesenchymal log2(TPM+1): 4.79
- Epithelial log2(TPM+1): 4.50
- Fold change: 0.29
- Status: No significant change
Selectivity landscape vs inhibition on YES1
Each point is one of the 92 approved drugs; color = inhibition % on YES1.
Mutation lollipop
Cancer-associated mutations plotted by residue position. Marker size + color scale with the number of distinct cancer reports.
Variants (1)
Mutation × cancer associations
| Mutation | Cancer | Organ | Source |
|---|---|---|---|
| T348I | osteosarcoma_bone | Bone | ref |
3D structure
Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.
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