Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0
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Comparative reversal scorer

Pick two cohorts. Returns drugs ranked by Δ-median reversal score (A − B). Drugs at the top selectively reverse cohort A but not B — biomarker-hypothesis candidates.

Pick two cohorts

Each cohort = a project + optional cancer_type/subtype filter. Both cohorts use the same operator T release + pathway library.

Cohort A

Cohort B