Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0· v2
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Midostaurin

45f8d363-bc76-5849-a0e8-dd1d52bc40a6 · FDA Approved · targets FLT3

Midostaurin

MeasuredReference

Midostaurin targets JAK3, MST2_STK3, PHKG1.

Primary targets

JAK3MST2_STK3PHKG1GLK_MAP4K3MLK3_MAP3K11

Top hallmarks

No hallmark data.

Top pathways disrupted

  • pi3k akt mtor signaling15.6k
  • apoptosis13.5k
  • apical junction13.4k

Resistance landscape — Midostaurin

MeasuredReference

No variant annotations found on Midostaurin's top targets.

No variant annotations on Midostaurin's top targets.
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