Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
KIRhub 2.0· v2
Ependymoma Hub
V1V2
Sign in
← Cases

Pirtobrutinib

85c57039-1913-54c5-86ea-9aba3af70241 · FDA Approved · targets BTK

Pirtobrutinib

MeasuredReference

Pirtobrutinib targets BTK, ERBB4_HER4, MAP2K2.

Primary targets

BTKERBB4_HER4MAP2K2PTK6YES_YES1

Top hallmarks

No hallmark data.

Top pathways disrupted

No pathway data.

Resistance landscape — Pirtobrutinib

MeasuredReference

5 known oncogenic variants exist on Pirtobrutinib's top targets — see detail for inhibition impact.

Open in new tab