Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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← Cases

ERBB2

RBC: ERBB2/HER2 · Substrate: pEY + Mn ·

Top inhibitors

MeasuredDerived
No inhibitors above threshold.

Known variants

Cancer associations

MutationCancer typeOrganSource
A775carcinoma_breastBreasthttps://doi.org/10.1158/2159-8290.CD-12-0095
D769Hcarcinoma_breastBreasthttps://www.mycancergenome.org/content/alteration/erbb2-d769h/
D769Ycarcinoma_breastBreasthttps://doi.org/10.1158/2159-8290.CD-12-0095
G776INSYVMAcarcinoma_lungLunghttps://www.cancer.gov/tcga.
G778INSCGcarcinoma_lungLunghttps://www.oncokb.org/gene/ERBB2/G778_S779insG?
P1170Acarcinoma_breastBreasthttps://www.cancer.gov/tcga.
P780carcinoma_breastBreasthttps://doi.org/10.1242/bio.047662
R896Ccarcinoma_breastBreasthttps://doi.org/10.1242/bio.047663
V777carcinoma_breastBreasthttps://doi.org/10.1158/2159-8290.CD-12-0095
V777Lcarcinoma_breastBreasthttps://depmap.org/portal.
V956Rcarcinoma_breastBreasthttps://depmap.org/portal.
Y781INSGSPcarcinoma_lungLunghttps://depmap.org/portal.
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