EGFR (d747-752/P753S)
Sign in to save this workspaceEGFR · Variant type: point · HGVS: p.P753S
Drug response on this variant
No drug-response measurements were cross-referenced for this variant.
Wild-type vs variant — drug response delta
Positive Δ means the drug hits the variant harder than wild-type (mutation-selective); negative Δ means it loses potency (resistance).
| Drug | Variant inh | WT inh | Δ (variant − WT) |
|---|
Cancer associations
| Cancer | Organ | Source |
|---|---|---|
| Skin Cancer | Skin | ref |
| malignant_melanoma_skin | Skin | ref |
| Wilms_tumour_kidney | Kidney | ref |
| carcinoma_skin | Skin | ref |
| carcinoma_lung | Lung | ref |
| malignant_melanoma_NS | Skin | ref |
| lymphoid_neoplasm_haematopoietic_and_lymphoid_tissue | Blood/Lymphatic System | ref |
| SKCM-US | Skin | ref |
| SKCM | Skin | ref |
Annotations
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