Apatinib — dose-response

MeasuredDerived

Dose-response curves across the assayed kinome. ← All drugs

Apatinib × GRK2

MeasuredDerived

IC50

71.28 nM

Hill slope

1.00

R²

-2.4510

Top kinases by potency

MeasuredDerived

Ordered by IC50 ascending (fitted).

Kinase	IC50
CSF1R	17.39 nM
KDR	32.34 nM
FLT4	36.73 nM
FLT1	45.99 nM
RAF1	58.79 nM
RET	71.15 nM
ACVR1B	71.28 nM
EPHA8	71.28 nM
FES	71.28 nM
GRK2	71.28 nM
GRK6	71.28 nM
MAP3K11	71.28 nM
MAPK13	71.28 nM
MELK	71.28 nM
MKNK1	71.28 nM
MYO3B	71.28 nM
NEK7	71.28 nM
PAK4	71.28 nM
PIM3	71.28 nM
PLK4	71.28 nM
CDK2+CCNA2	71.28 nM
BMX	71.28 nM
TESK2	71.28 nM
TGFBR2	71.28 nM
TSSK3	71.28 nM
ULK1	71.28 nM
VRK2	71.28 nM
WEE1	71.28 nM
KIT	86.27 nM
SRMS	155.12 nM