Crizotinib — dose-response

Dose-response curves across the assayed kinome. ← All drugs

Crizotinib × MAP4K1

IC50

18.17 nM

Hill slope

0.95

R²

0.9963

Top kinases by potency

Ordered by IC50 ascending (fitted).

Kinase	IC50
STK11	0.22 nM
CHUK	0.35 nM
CSNK1A1	0.50 nM
NEK6	0.51 nM
CSNK2A1	0.64 nM
PDPK1	0.74 nM
ROS1	0.79 nM
MAPKAPK3	1.24 nM
NTRK3	1.37 nM
CSNK1G3	1.41 nM
CDC7	2.09 nM
MAPKAPK2	2.10 nM
MAP3K21	2.27 nM
DAPK3	4.34 nM
KSR2	4.68 nM
ALK	4.96 nM
KSR1	5.90 nM
CSNK1E	6.22 nM
MET	9.52 nM
IKBKB	10.73 nM
HIPK2	11.76 nM
MATK	12.39 nM
MERTK	17.04 nM
MAP4K1	18.17 nM
PIM2	18.37 nM
PRKCI	19.25 nM
MST1R	19.96 nM
MUSK	22.53 nM
AXL	23.85 nM
LIMK1	26.05 nM