Erlotinib — dose-response

MeasuredDerived

Dose-response curves across the assayed kinome. ← All drugs

Erlotinib × CHEK1

MeasuredDerived

IC50

159.95 nM

Hill slope

0.80

R²

0.1480

Top kinases by potency

MeasuredDerived

Ordered by IC50 ascending (fitted).

Kinase	IC50
EGFR	1.15 nM
MATK	71.28 nM
PRKCA	71.28 nM
CDC7	71.28 nM
CDK4+CCND1	71.28 nM
EPHB3	71.28 nM
PLK2	71.28 nM
MYO3A	71.28 nM
HIPK3	71.28 nM
MAP2K6	71.28 nM
TTBK2	71.28 nM
MAP3K21	71.28 nM
MAPK12	71.28 nM
DDR1	83.05 nM
STK10	110.93 nM
MAPK13	155.12 nM
CDK2+CCNA1	156.17 nM
PBK	156.91 nM
CHEK1	159.95 nM
MAP2K7	170.70 nM
ACVR1B	174.18 nM
PRKCH	215.76 nM
PLK1	220.11 nM
FGFR2	258.08 nM
ABL2	358.35 nM
FLT4	380.03 nM
SLK	411.94 nM
FLT3	463.45 nM
ABL1	544.42 nM
RET	737.36 nM