Lapatinib — dose-response

MeasuredDerived

Dose-response curves across the assayed kinome. ← All drugs

Lapatinib × ULK2

MeasuredDerived

IC50

71.28 nM

Hill slope

1.00

R²

-2.4513

Top kinases by potency

MeasuredDerived

Ordered by IC50 ascending (fitted).

Kinase	IC50
EGFR	20.78 nM
ERBB2	61.63 nM
ULK2	71.28 nM
ULK1	71.28 nM
STK16	71.28 nM
PRKACB	71.28 nM
GRK3	71.28 nM
DAPK2	71.28 nM
IKBKE	71.28 nM
OXSR1	71.28 nM
NEK7	71.28 nM
MAP2K6	71.28 nM
MAP3K21	71.28 nM
MAP3K7	71.28 nM
ERBB4	72.96 nM
MAP2K2	156.23 nM
MAPKAPK3	156.39 nM
HIPK1	156.68 nM
MST1R	156.79 nM
DAPK3	157.01 nM
CDC42BPG	157.16 nM
NEK6	166.85 nM
TAOK2	187.73 nM
KIT	219.35 nM
MAPK7	222.12 nM
CAMKK2	1.035 μM
PBK	1.036 μM
MAP2K5	1.049 μM
PLK1	1.091 μM
CSNK2A2	1.098 μM