Neratinib — dose-response

Dose-response curves across the assayed kinome. ← All drugs

Neratinib × STK26

IC50

22.95 nM

Hill slope

1.07

R²

1.0000

Top kinases by potency

Ordered by IC50 ascending (fitted).

Kinase	IC50
MAP4K5	0.46 nM
ERBB4	0.92 nM
EGFR	1.55 nM
MAP4K3	5.20 nM
MERTK	13.43 nM
STK26	22.95 nM
ERBB2	26.34 nM
STK24	26.94 nM
STK25	27.30 nM
TNIK	38.19 nM
BLK	39.56 nM
LCK	48.00 nM
YES1	53.43 nM
MAP4K1	67.27 nM
STK4	67.99 nM
CDK5+CDK5R1_P35	71.28 nM
PHKG2	71.28 nM
PIM3	71.28 nM
PRKCE	71.28 nM
GRK2	71.28 nM
CSNK2A1	71.28 nM
CDK2+CCNO	71.28 nM
STK3	88.44 nM
TNK2	92.27 nM
AXL	93.86 nM
NUAK2	97.58 nM
MINK1	98.06 nM
MAP2K2	113.21 nM
MAP4K4	118.91 nM
SIK1	140.09 nM