Nintedanib — dose-response

Dose-response curves across the assayed kinome. ← All drugs

Nintedanib × MELK

IC50

1.77 nM

Hill slope

1.05

R²

1.0000

Top kinases by potency

Ordered by IC50 ascending (fitted).

Kinase	IC50
FLT4	1.27 nM
MELK	1.77 nM
LCK	2.18 nM
RET	2.34 nM
DDR2	2.84 nM
KDR	4.82 nM
NTRK3	5.78 nM
YES1	5.81 nM
DDR1	7.67 nM
PDGFRA	8.04 nM
SIK2	8.10 nM
BTK	11.49 nM
ABL1	13.80 nM
LYN	14.18 nM
BLK	14.49 nM
FGFR2	14.82 nM
SRC	15.80 nM
PDGFRB	16.51 nM
CSF1R	18.27 nM
NTRK1	19.37 nM
PEAK1	20.68 nM
FGR	21.26 nM
FYN	24.56 nM
STK10	27.79 nM
MAP2K5	29.69 nM
JAK3	36.14 nM
FER	36.32 nM
LYN_2	38.63 nM
SIK1	40.10 nM
FGFR1	40.67 nM