Regorafenib — dose-response

Dose-response curves across the assayed kinome. ← All drugs

Regorafenib × MAPK15

IC50

119.41 nM

Hill slope

1.55

R²

1.0000

Top kinases by potency

Ordered by IC50 ascending (fitted).

Kinase	IC50
RAF1	12.37 nM
RET	13.82 nM
ARAF	15.20 nM
HIPK4	21.15 nM
MAP3K20	25.39 nM
CSF1R	27.14 nM
PDGFRA	27.15 nM
DDR2	35.21 nM
KDR	51.30 nM
PDGFRB	57.23 nM
BRAF	62.68 nM
FLT1	71.14 nM
AKT1	71.28 nM
INSR	71.28 nM
KSR2	71.28 nM
MAP2K6	71.28 nM
MARK2	71.28 nM
MYLK3	71.28 nM
NEK7	71.28 nM
ERBB2	71.28 nM
PLK1	71.28 nM
PRKCE	71.28 nM
BMX	71.28 nM
STK11	71.28 nM
STK25	71.28 nM
STK32C	71.28 nM
FLT4	79.32 nM
DDR1	98.20 nM
MAPK15	119.41 nM
DSTYK	154.17 nM