Tivozanib — dose-response

Dose-response curves across the assayed kinome. ← All drugs

Tivozanib × AURKC

IC50

40.51 nM

Hill slope

0.83

R²

1.0000

Top kinases by potency

Ordered by IC50 ascending (fitted).

Kinase	IC50
FLT4	1.78 nM
KDR	2.37 nM
RET	2.97 nM
CSF1R	4.00 nM
FRK	6.76 nM
PDGFRA	7.60 nM
STK10	8.98 nM
PDGFRB	9.91 nM
LCK	10.65 nM
LYN	13.23 nM
EPHB2	16.35 nM
FLT1	16.75 nM
FGR	19.85 nM
EPHA6	23.66 nM
ABL1	26.77 nM
LYN_2	26.85 nM
DDR2	31.01 nM
HCK	31.99 nM
AURKB	35.64 nM
EPHA2	36.56 nM
NTRK3	38.21 nM
EPHA5	38.83 nM
ABL2	39.65 nM
PTK6	39.71 nM
AURKC	40.51 nM
EPHB4	40.79 nM
KIT	44.83 nM
EPHB1	46.57 nM
MAP4K5	52.61 nM
DDR1	53.29 nM