ACVR1(ALK2/ACVR1)
Sign in to save this workspaceUniProt Q04771 · PDB · AlphaFold · Substrate: Casein + Mn · Clone: cytoplasmic aa145-509
Top inhibitors
| # | Drug | Inhibition | Residual | KISS | Gini |
|---|
Paralog block
No paralog group registered for this kinase.
EMT expression
- Mesenchymal log2(TPM+1): 4.80
- Epithelial log2(TPM+1): 3.14
- Fold change: 1.66
- Status: Upregulated
Selectivity landscape vs inhibition on ACVR1
Each point is one of the 92 approved drugs; color = inhibition % on ACVR1.
Variants (2)
3D structure
Embedded NGL viewer pulls a representative PDB entry (or AlphaFold model if no experimental structure is registered). Heavy bundle — loaded only on demand.
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