Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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80cb0e05-387d-4bd8-b49c-ff2aae043982

07bb3ce4-9227-5373-8f40-cfb42a87cdb3

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype
age_years
67

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • INFLAMMATORY_RESPONSE+0.530
  • ALLOGRAFT_REJECTION+0.510
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.490
  • HEDGEHOG_SIGNALING+0.490
  • INTERFERON_GAMMA_RESPONSE+0.490
  • INTERFERON_ALPHA_RESPONSE+0.480
  • ANGIOGENESIS+0.470
  • IL6_JAK_STAT3_SIGNALING+0.460
  • TNFA_SIGNALING_VIA_NFKB+0.460
  • UV_RESPONSE_DN+0.450

Top 10 suppressed

  • OXIDATIVE_PHOSPHORYLATION-0.580
  • MYC_TARGETS_V2-0.570
  • E2F_TARGETS-0.520
  • MYC_TARGETS_V1-0.470
  • DNA_REPAIR-0.460
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.420
  • G2M_CHECKPOINT-0.400
  • CHOLESTEROL_HOMEOSTASIS-0.380
  • MTORC1_SIGNALING-0.380
  • UNFOLDED_PROTEIN_RESPONSE-0.370

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1c277dab0-361f-4aa6-96b1-522a6e556ae1
colon-landscapes@1
0.954
22cec663c-00c8-48b5-967b-f2a53c0fb409
colon-landscapes@1
0.950
3ec054d40-e5b8-496a-8c99-5e7f88f2cf37
colon-landscapes@1
0.949
4TCGA-CR-7376-01A-11R-2132-07
head-neck@1
0.948
5C3N-02923
lung-landscapes@6
cohortMD20.932
667ed15bc-bbe5-4da7-81f9-002c54483f67
colon-landscapes@1
0.931
7TCGA-A2-A25A-01A-12R-A16F-07
breast-umap@18
A0.927
8a307b24f-4caa-403a-8313-2a4604f2079a
colon-landscapes@1
0.927
9f22cfa82-a346-4fed-bc81-21a29bf990ee
colon-landscapes@1
0.926
106dfa748c-af43-469f-a98b-8472a4132739
melanoma-umap@29
0.926