SRR1375571
GTEX
Clinical attributes
From the source cohort, normalized into canonical keys plus the project's native columns.
- cancer_type
- GTEX
- cancer_type_detailed
- —
- subtype
- —
- cancer_type
- GTEX
- sex
- Male
GSVA pathway preview (0 Hallmark scores)
Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.
Patient twins — nearest pathway neighbors
10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.
7 twins match this tumor's tissue · 3 come from a different tissue of origin
| # | Sample | Cancer type | Subtype | cos similarity |
|---|---|---|---|---|
| 1 | SRR1381889 | GTEX | — | 0.953 |
| 2 | SRR1470703 | GTEX | — | 0.951 |
| 3 | BS_AJ6X83G5 | DNET | — | 0.948 |
| 4 | SRR1317877 | GTEX | — | 0.948 |
| 5 | SRR1320115 | GTEX | — | 0.946 |
| 6 | SRR1318163 | GTEX | — | 0.942 |
| 7 | SRR1310008 | GTEX | — | 0.942 |
| 8 | BS_TG93XC55 | Ganglioglioma | — | 0.936 |
| 9 | BS_WCRKYV0T | low-grade glioma | — | 0.936 |
| 10 | SRR1480059 | GTEX | — | 0.933 |
Per-pathway drug coverage
For each elevated pathway in this tumor, the best-reversing drug across the catalog. Uncovered pathways = unmet need at pathway level for this one patient.
0 of 11 elevated pathways have at least one drug that meaningfully reverses them.
| Pathway (elevated) | tumor score | Best drug | reversal magnitude |
|---|---|---|---|
| PANCREAS_BETA_CELLS | 0.453 | Cobimetinib | — uncovered |
| KRAS_SIGNALING_DN | 0.424 | Remibrutinib | — uncovered |
| SPERMATOGENESIS | 0.313 | Inavolisib | — uncovered |
| HEDGEHOG_SIGNALING | 0.230 | Inavolisib | — uncovered |
| UV_RESPONSE_DN | 0.216 | Inavolisib | — uncovered |
| OXIDATIVE_PHOSPHORYLATION | 0.194 | Remibrutinib | — uncovered |
| ESTROGEN_RESPONSE_EARLY | 0.118 | Inavolisib | — uncovered |
| APICAL_SURFACE | 0.098 | Temsirolimus | — uncovered |
| MYOGENESIS | 0.083 | Inavolisib | — uncovered |
| ESTROGEN_RESPONSE_LATE | 0.081 | Idelalisib | — uncovered |
| BILE_ACID_METABOLISM | 0.036 | Inavolisib | — uncovered |