Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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0e1f24b3-fc2b-5d35-ac80-96f1d833af54

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
cancer_type_detailed
subtype

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • PANCREAS_BETA_CELLS+0.400
  • ANGIOGENESIS+0.300
  • UV_RESPONSE_DN+0.300
  • NOTCH_SIGNALING+0.200
  • TGF_BETA_SIGNALING+0.200
  • EPITHELIAL_MESENCHYMAL_TRANSITION+0.100
  • HEDGEHOG_SIGNALING+0.100
  • UNFOLDED_PROTEIN_RESPONSE+0.100
  • WNT_BETA_CATENIN_SIGNALING+0.100
  • ANDROGEN_RESPONSE+0.000

Top 10 suppressed

  • E2F_TARGETS-0.500
  • ALLOGRAFT_REJECTION-0.400
  • G2M_CHECKPOINT-0.400
  • INTERFERON_ALPHA_RESPONSE-0.400
  • INTERFERON_GAMMA_RESPONSE-0.400
  • MYC_TARGETS_V2-0.400
  • OXIDATIVE_PHOSPHORYLATION-0.400
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.400
  • COMPLEMENT-0.300
  • DNA_REPAIR-0.300

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

10 twins match this tumor's tissue · 0 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1fe036511-fe82-467c-9c6e-59bfb8b0a329
melanoma-umap@29
0.857
2TCGA-78-7161-01A-11R-2039-07
lung-landscapes@6
cohortA30.850
3C3L-02165
lung-landscapes@6
cohortA20.833
4SRR10900003
melanoma-umap@29
0.827
5BSR_08_0188_C3_S52
breast-umap@18
A0.824
6TCGA-BH-A0EI-01A-11R-A115-07
breast-umap@18
B0.820
7TCGA-AO-A12C-01A-11R-A10J-07
breast-umap@18
A0.815
8C3L-03463
lung-landscapes@6
cohortA30.814
9SRR8518225
breast-umap@18
B0.812
10e3d71c3f-4e56-45fa-be88-2cf444b70a5c
melanoma-umap@29
0.809