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MDT-AP-0592

Med · Medulloblastoma

1e0d3239-d2c2-5596-87e1-61c1e51cd74f

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
Med
cancer_type_detailed
subtype
Medulloblastoma
cancer_type
Med
subtype
Medulloblastoma
overall_survival_months
51
os_event
false
age_years
7
sex
M
new_clusters
S2
umap1_2d
-0.657248168
umap2_2d
-8.797555197
umap1_3d
-3.773682018
umap2_3d
-1.668158008
umap3_3d
6.817317982
dataset
Med-Taylor

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • MITOTIC_SPINDLE+0.350
  • APICAL_SURFACE+0.340
  • CHOLESTEROL_HOMEOSTASIS+0.340
  • WNT_BETA_CATENIN_SIGNALING+0.310
  • MTORC1_SIGNALING+0.300
  • PANCREAS_BETA_CELLS+0.290
  • HEDGEHOG_SIGNALING+0.280
  • NOTCH_SIGNALING+0.260
  • GLYCOLYSIS+0.230
  • UNFOLDED_PROTEIN_RESPONSE+0.230

Top 10 suppressed

  • INTERFERON_ALPHA_RESPONSE-0.430
  • INTERFERON_GAMMA_RESPONSE-0.410
  • ALLOGRAFT_REJECTION-0.390
  • INFLAMMATORY_RESPONSE-0.320
  • IL6_JAK_STAT3_SIGNALING-0.290
  • KRAS_SIGNALING_UP-0.270
  • COMPLEMENT-0.230
  • COAGULATION-0.210
  • TNFA_SIGNALING_VIA_NFKB-0.210
  • P53_PATHWAY-0.100

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

9 twins match this tumor's tissue · 1 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1MDT-AP-0007
medullo-epn-umap@date-based
MedMedulloblastoma0.815
2TCGA-92-7341-01A-31R-2045-07
lung-landscapes@6
cohortSQ20.803
3SRR1313118
breast-umap@18
B0.800
4TCGA-85-6798-01A-11R-1949-07
lung-landscapes@6
cohortSQ20.793
5TCGA-BH-A0HY-01A-11R-A056-07
breast-umap@18
C0.788
6TCGA-51-4081-01A-01R-1100-07
lung-landscapes@6
cohortSQ20.778
7TCGA-C8-A12Z-01A-11R-A115-07
breast-umap@18
C0.777
8TCGA-94-A5I6-01A-21R-A27Q-07
lung-landscapes@6
cohortSQ20.762
9BS_WGK8ZMVA
brain-umap@2
Supratentorial Ependymoma0.761
10TCGA-43-7657-01A-31R-2125-07
lung-landscapes@6
cohortSQ10.755