Research Use Only. KIRhub outputs are computational research artifacts. They are not validated for clinical decision-making, diagnosis, or treatment.
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BS_23QW0BBA

high-grade glioma

2193cf3b-7ab1-5050-a9bb-bc95423c4652

Score in workbench →

Clinical attributes

From the source cohort, normalized into canonical keys plus the project's native columns.

cancer_type
high-grade glioma
cancer_type_detailed
subtype
cancer_type
high-grade glioma
overall_survival_months
272.04336399474374
age_years
9.863
sex
Female

GSVA pathway preview (50 Hallmark scores)

MeasuredDerivedReference

Top 10 most elevated and top 10 most suppressed Hallmark pathways for this sample.

Top 10 elevated

  • E2F_TARGETS+0.536
  • G2M_CHECKPOINT+0.534
  • ANGIOGENESIS+0.503
  • MYC_TARGETS_V2+0.435
  • MYC_TARGETS_V1+0.394
  • TNFA_SIGNALING_VIA_NFKB+0.372
  • HEDGEHOG_SIGNALING+0.370
  • MTORC1_SIGNALING+0.340
  • UV_RESPONSE_UP+0.321
  • MITOTIC_SPINDLE+0.316

Top 10 suppressed

  • INTERFERON_GAMMA_RESPONSE-0.240
  • INTERFERON_ALPHA_RESPONSE-0.200
  • FATTY_ACID_METABOLISM-0.138
  • KRAS_SIGNALING_DN-0.126
  • BILE_ACID_METABOLISM-0.123
  • REACTIVE_OXYGEN_SPECIES_PATHWAY-0.110
  • MYOGENESIS-0.104
  • PEROXISOME-0.103
  • XENOBIOTIC_METABOLISM-0.094
  • ALLOGRAFT_REJECTION-0.069

Patient twins — nearest pathway neighbors

MeasuredDerived

10 samples closest to this one in 50-dim pathway space, drawn from the Pathway Atlas. Cosine similarity = 1 means identical pathway state.

8 twins match this tumor's tissue · 2 come from a different tissue of origin

#SampleCancer typeSubtypecos similarity
1BS_1D6PZNKN
brain-umap@2
Diffuse intrinsic pontine glioma0.848
2BS_7327SDAQ
brain-umap@2
high-grade glioma0.839
3SRR934906
brain-umap@2
0.827
4726D58A7-23E0-492A-B5CE-15DCB11B0C90
brain-umap@2
0.826
5TCGA-77-7337-01A-21R-2045-07
lung-landscapes@6
cohortSQ10.826
6TCGA-H7-8502-01A-11R-2403-07
head-neck@1
0.824
7TCGA-ZF-AA4N-01A-11R-A38B-07
bladder-landscape@3
0.822
8MNG402
mng-umap@100
0.817
9SRR15030851
colon-landscapes@1
0.815
10BS_F6V1Y4QS
brain-umap@2
Glial-neuronal tumor NOS0.809